The ultimate destruction is a technique when the player holds down the left mouse button and rapidly scrolls the mouse wheel. This will rapidly fire 3 - 4 of your weapons as you scroll through them. The technique works best with powerful explosive weapons such as the Pequeno-R25, p25 maisto, dragon destructor, dominator, etc. Since most of your shots will go up, the technique works very well on enemies above you, such as the Hell Bearer, crabocalypse, or sling raider.